15:49 | 21st November 2017

World News:

Fri 20 May, 2016
By Editor


Now researchers in the US have revealed they used gene-editing technology to remove DNA of the commonest HIV-1 strain from several organs of infected mice and rats.

Latest Headlines

Youth Invited to Design Social Media Strategy for UNAIDS

The United Nations has invited young people to create and shape the new UN strategy on youth and HIV/AIDS through an online collaborative project launched Tuesday, according to an article on the UN website


Blood donation center rejects straight man because he 'appeared' gay

A 22-year-old straight man was refused the right to donating blood after staff at a blood bank believed the man ‘seemed’ gay.


Nicki Minaj and Ricky Martin new faces of MAC Viva Glam HIV/AIDS campaign

Nicki Minaj and Ricky Martin have been announced as the faces of the 2012 MAC Viva Glam campaign to fight HIV/AIDS.


UNAIDS and WHO hail new results for Once - daily pill for HIV Negative people

New data from studies in Kenya, Uganda and Botswana confirm major role of antiretroviral medicine in preventing heterosexual HIV transmission


Are We One Step Closer to a Cure For HIV?

Scientists have managed to remove DNA of the HIV virus from living tissue for the first time in a breakthrough that could lead to an outright cure.

At the moment, treating the disease involves the use of drugs that suppress levels of the virus so the body’s immune system can cope.

Now researchers in the US have revealed they used gene-editing technology to remove DNA of the commonest HIV-1 strain from several organs of infected mice and rats.

In April, the same team reported that they had successfully eliminated the virus from human cells in the laboratory, but a paper in the journal Nature Gene Editing revealed they had managed to do the same thing in live animals for the first time.



The researchers’ team leader, Professor Kamel Khalili, of Temple University, said: “In a proof-of-concept study, we show[ed] that our gene-editing technology can be effectively delivered to many organs of two small animal models and excise large fragments of viral DNA from the host cell genome.”

The current antiretroviral drugs for HIV are not able to eliminate HIV-1 from the infected cells.

And if treatment is interrupted, the virus can start replicating quickly, putting patients of risk of getting full-blow AIDS.

This is because it is able to persist in immune system T-cells and other places where it is not actually active and is unaffected by the current treatments.

The researchers used a specially adapted virus to deliver the gene-editing system into the cells.

“The ability of the rAAV delivery system to enter many organs containing the HIV-1 genome and edit the viral DNA is an important indication that this strategy can also overcome viral reactivation from latently infected cells and potentially serve as a curative approach for patients with HIV,” Professor Khalili said.

To read more, click www.independent.co.uk/news/science/hiv-aids-cure-virus-disease-dna-genes-temple-university-research-gene-editing-a7037571.html

Source: The Independent

 

Back to previous page

cialis